Il continuo monitoraggio del virus SARS-CoV-2 e delle sue varianti, tramite unica PCR, è lo strumento più efficace nelle mani dei sistemi sanitari mondiali per mantenere sotto controllo il virus responsabile della CoViD-19 ed intercettare sul nascere nuovi focolai. ...
Omicron-2, the “stealth” variant is becoming prevalent in Denmark and in many Asian countries
Jan 17, 2022 | COVID-19 Insights
Omicron or B.1.1.529, the last “version” of SARS-CoV-2 original strain, was identified almost two months ago. Today, Omicron is going to replace Delta variant prevalence in almost all countries. According to ECDC monitor of Gisaid data, at the moment we write,...
SGTF versus N501Y mutation detection in the diagnosis of the Omicron variant’s two clades: BA.1 and BA.2
Dec 16, 2021 | COVID-19 Insights
Omicron tracked in 77 countries The latest WHO weekly report, dated 12/13/2021 reveals that the number of people affected by Omicron is increasing sharply worldwide. Omicron variant is characterised by more than 30 mutations in Spike region and has been split into two...
Individuata una nuova forma di Omicron invisibile ad alcuni KIT PCR: l’OMS sta valutando la separazione in BA.1 e BA.2
Dec 9, 2021 | COVID-19 Insights
Nuova forma di variante Omicron Una nuova versione della variante Omicron (B.1.1.529) è stata recentemente messa sotto i riflettori dal gruppo Pango-designation, dopo che in pochissimi giorni decine di nuove rilevazioni sono state depositate nel database Gisaid,...
RT- PCR, the gold standard in CoViD-19 diagnosis: the most common pitfalls and their interpretations
Oct 5, 2021 | COVID-19 Insights
The gold standard for SARS-CoV-2 diagnosis is the Reverse Transcriptase Polymerase Chain Reaction, aka RT-PCR or qRT-PCR. This technique has been introduced in 1983 (Saiki et al. 1985) and nowadays is widely used in the diagnosis of many pathologies, from infectious...
Delta Variant outbreak emergency: what and where
Aug 4, 2021 | COVID-19 Insights
As the media have been writing for weeks, the DELTA variant (born as variant B.1.617.2), first identified in mid-2020, is spreading fast. According to last ECDC commentary, the highly infectious variant of concern (V.O.C.) DELTA is becoming “dominant in much of the...
First in vivo evidence of escape of SARS-CoV-2 South Africa variant from natural and vaccine-induced sera
Jun 3, 2021 | COVID-19 Insights, OaCP
Months after the first SARS-CoV-2 variant has been sequenced, many scientific works have largely hypothesized the clinical impact of the mutations, based on in silico experiments. Starting point The role of SARS-CoV-2 mutations has been supposed to impact the immune...
COVID-19, variante messicana (mutazione T478K) scoperta dall’Unibo
May 11, 2021 | COVID-19 Insights, OaCP, Press
Il nostro R&D Manager, Simone Di Giacomo, in collaborazione con il Laboratorio di Genomica Computazionale guidato dal prof. Federico Giorgi presso il Dipartimento di Farmacia e Biotecnologia ha scoperto una nuova mutazione a carico del virus SARS-CoV2, la T478K....
Changes in the Receptor Binding Domain (RBD) of Sars-CoV-2 and their clinical impacts
Apr 30, 2021 | COVID-19 Insights, OaCP
All Sars-CoV-2 Variants of Concern (VOC) such as B.1.1.7 (aka UK) or B.1.351 (aka South African) harbor typical and own patterns of mutations, also out of the Spike glycoprotein. B.1.1.7 contains 21 among missense mutations and deletions which 9 within Spike gene (del...
The challenge of monitoring Sars-CoV-2 variants cannot be met just by sequencing technology
Apr 7, 2021 | COVID-19 Insights, OaCP
Months ahead of forced coexistence with Sars-CoV-2, when we thought we knew the virus intimately and profoundly by hundreds of scientific works and hundreds of miles of sequencing reads, here the variants made their appearance. Nothing new, nothing unexpected. Brand...
Back to menu
